Not a cliffhanger - there was no real sense of urgency in the epilogue. It was penned more like a bittersweet ending.
There are technically no loose ends after the movie, so, yes, if Bandai/Sunrise decide to rest on their laurels and let things stand as such, SEED Freedom could constitute the definitive end to the SEED saga. It does wrap up a few things, especially on the character relations side.
As for the afterword, no; Liu Goto mainly talks about the imagery driving some of his writing or being the backbone for certain scenes.
The only clue is that Fukuda (on his Twitter account? or it might have been in one of the post-movie interviews) said that he doesn't believe Kira and Lacus will ever "retire". That said, this reads as personal opinion, not an official response.