Personally, my main issue with the spoilers are the larger plot points rather than the companion's fates. Bioware still has not broken out of its reliance for random twists for the shock factor and magic buttons. As far as gameplay, I personally found ME2 far too repetitive.
It is not worth my money if I know I will not enjoy it. Personally I like some of the characters a lot, such as Tali, but I would rather save my money and watch what happens to her over youtube.
edit: I would still love to hear your opinion of it though. So do tell me what you think of it.